For an oocyte to become All set for fertilization and growth into an embryo, the right list of genes has to be turned on. Namekawa suspected this pre-programming from the oocyte genome occurs in several phases — the main 1 starting up across the time a woman is born. He believed that chromatin remodeling proteins did A lot of this function, by shifting spools around.
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Using the GCRLE grant, Munakata and Namekawa will seem extra carefully at how oocytes are genomically primed and stored for afterwards use. They can investigate the purpose of a chromatin remodeler in oocyte survival and fertility.
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Yasuhisa Munakata, a postdoctoral fellow in the College of Biological Sciences, has been given a grant to study how egg cells in the ovary modify after some time.
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